Research Spotlight (VHIR): Anti-cancer drug delivery in polymeric micelles

Click to read the full press release on the VHIR website

Our EVO-NANO colleagues at the Vall d’Hebron Institut de Recerca have recently published work in connection with our project – using Zileuton™, a drug originally prescribed for asthma, it has been found to be a particularly powerful anti-cancer drug against aggressive tumours such as types of breast cancer.

The transport of this drug into tumour cells in live mouse trials was achieved by encasing it in polymeric micelles, which improves both the initial delivery method of injection, and eventual uptake by the cells. It was found to reduce not only the cancer cells themselves, but also the circulating cancer stem cells, which are responsible for metastasis. Hence, this could be a chemotherapy drug that effectively applies to metastatic tumours as well as primaries.